metaP
SortMotifDisovery
Sorting Motif Database
degprune
aag encoding
degPareto

Protein Sorting Motif Database (PZipcode)


Motivation

A single cell has about 1 billion proteins. How these proteins are transported to their target location after their translation in cytoplasm is a mystery. This project aims to build a database and algorithms to search, retrieve, and visualize protein sorting motifs of all species.

Results

We have developped successfuly our first version de novo protein sorting motif discovery algorithms.They have been used to rediscover a series of protein sorting signals. It thus has great potential to generate hypothesis for biologists involved in cellular traffic analysis. We have also built a protein sorting motif database collecting known sorting signals into a well-organized hub for easy access.

Conclusions



Software/Server availability

Protein Sorting Motif Database

Sorting motif discovery server